Police were called to the 7900 block of Ayers Road in Anderson Township just before 8:30 p.m. Monday, the Hamilton County Sheriff's Office said.
A child was transported to Cincinnati Children's Hospital Medical Center with non-life-threatening injuries, it said.
It is unclear whether or how Mixon, 26, is involved. Mixon's representative and the Bengals did not immediately respond to requests for comment.
Authorities said sheriff's deputies obtained a search warrant for the home "and were able to gather evidence that will be part of this active investigation." "Our detectives will continue to review this evidence diligently and conduct interviews," the sheriff's office said in a statement, adding that it hopes to have an update later this week. It declined to respond to additional questions.
Mixon was charged at the same home in February and accused of pointing a gun at a woman and threatening her, NBC affiliate WLWT of Cincinnati reported.
The charge was dismissed, and the case was reassigned, according to WLWT, which said it was unclear whether Mixon lives at the property, which a trust listed as the owner.